The syringe filter is a single-use (disposable) for the purpose of remove of particulate impurities from solvent/reagent before analysis used by HPLC, GC, and dissolution testing.
Syringe filters are used to separate molecules based on their binding properties. The filters are usually made of hydrophobic polymers such as polytetrafluoroethylene(PTFE), polypropylene(PP), cellulose acetate(CA), Polyvinylidene Fluoride (PVDF), Polyethersulfone (PES), Regenerated cellulose (RC), and Nylon. And are widely used in the field of HPLC for sample concentration and separation.
With the use of hydrophilic filters, numerous water purification methods are made more efficient. These material types are used in a variety of processes including desalination, cleanse and purify water for medical purposes, refine oil, and various other chemical processes. A hydrophilic filter is a type of filter used in the filtration process. This type of filter uses materials that are attracted to water, opposed to repelled by it. Hydrophilic filters are typically used in liquid filtration processes because they improve the efficiency of the process.
Hydrophilic materials tend to attract water aqueous solutions that allow polar liquids to pass through rather than hydrophobic materials that are water-hating. And the pore size, diameter also affect the solution.
Finally, choosing a sterile or non-sterile syringe filter also depends on the sample’s processing application. Sterile is commonly packaged in individual packing, and if you just want to directly apply the liquids with sterilization then this is the best choice and vice versa.
Syringe Filter operation process:
- Choose a proper connection port with disposable syringes filter and glass syringes, first put the filter on the syringe, then put the liquid body into the syringe, press down the pushrod and collect the filtered liquid.
- It's better to choose a suitable glass syringe of more than 10cc because the limited volume causes the pressure to exceed the volume, resulting in the destruction of the filter membrane.
- Remember to laboratory use only, single-use, and non-renewable.
- It's important to filter out impurities prior to injection, which is equivalent to dead volume of the syringe filter. (25mm, 1-2mL)
